The Tribeca Film Festival Guide describe The Yacoubian Building  as “The most expensive Egyptian film ever made, The Yacoubian Building is a sprawling, star-studded epic that spans all the social classes populating contemporary Cairo.”

The Guide also mentioned that the film “ ..dramatizes topical issues like adultery, political corruption, Islamist terrorism, and the hitherto taboo subject of homosexuality. First-time director Marwan Hamed crafts a gripping drama out of Alaa Al Aswani's novel, an Arabic-language bestseller already in its 12th printing. The famous Yacoubian Building was constructed in downtown Cairo in 1937 to house the city's upper crust. Today the tenants of its spacious apartments are a bit down-in-the-dumps, while its rooftop laundry rooms have been converted into homes for the poor.”

The plot of the film was explained as “The main characters include Zaki Pasha (Adel Imam), an aging playboy who represents a vanishing world of gentility; a French singer and his former love Christine (Yousra); and Bosaina (Hind Sabry), a pretty, disillusioned girl who lives on the roof. The growing influence of Islam in Egypt is dramatized through two controversial storylines. The doorman's son Taha (Mohamed Imam), frustrated in his attempts to move up in society, turns to religious fanaticism and ends up training for jihad in a desert camp. Meanwhile, the religious piety of Haj Azzam (Nour El Sherif), who has risen from shoeshine boy to rich businessman, is exposed as a sham that hides only self-interest.”

The guide highlighted the homosexuality issue by saying : “The film's frank treatment of homosexuality in the relationship between a newspaper editor and a young soldier is revolutionary in the context of Egyptian cinema.”